Cerebral Amyloid Angiopathy-Related Transient Focal Neurologic Episodes
نویسندگان
چکیده
منابع مشابه
Cerebral amyloid angiopathy and transient focal neurological episodes.
next most common clinical presentation of CAA after ICH. TFNEs were recurrent, stereotyped, brief (usually <30 min) but had a very wide clinical spectrum: although about half were positive (‘auralike’) spreading somatosensory or visual symptoms, the other half were predominantly negative symptoms, resembling ‘classic’ TIAs (e.g. hemiparesis or dysphasia), in keeping with the observations by Pat...
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BACKGROUND AND PURPOSE Transient focal neurological episodes (TFNE) are recognized in cerebral amyloid angiopathy (CAA) and may herald a high risk of intracerebral hemorrhage (ICH). We aimed to determine their prevalence, clinical neuroimaging spectrum, and future ICH risk. METHODS This was a multicenter retrospective cohort study of 172 CAA patients. Clinical, imaging, and follow-up data wer...
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Vascular inflammation is present in a subset of patients with cerebral amyloid angiopathy (CAA) and has a major influence in determining the disease manifestations. Radiological characterization of this subset is particularly important to achieve early recognition and treatment. We conducted this study to investigate the role of imaging in differentiating CAA with and without inflammation. We r...
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A 59-year-old man was arrested for unruly public behavior. He was subsequently found unresponsive with bilateral upper extremity extensor posturing and lower extremity triple flexion when stimulated. Over the next 48 hours, he awoke and became belligerent. MRI revealed innumerable cortical microhemorrhages on susceptibility-weighted imaging (figure, A) and asymmetric subcortical T2 hyperintensi...
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The relationship between amyloid beta-protein (A beta) length and the apolipoprotein E (APOE) epsilon 2 allele, which is over-represented in cerebral amyloid angiopathy-related haemorrhage (CAAH), has not previously been examined. Of 57 CAA patients studied, 37 had CAAH. All patients, particularly those with CAAH had more blood vessels immunoreactive for A beta 40 than A beta 42 in both the lep...
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ژورنال
عنوان ژورنال: Neurology
سال: 2021
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000012234